Ethoxycarbonyl Group

Ethoxycarbonyl Group

SCHEMBL28072241

CCOC=O.O=[N+]([O-])c1c[nH]c2ccccc12

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.43
MAPT P10636 6/20 0.43
MEN1 O00255 5/20 0.43
NPC1 O15118 3/20 0.43
GAA P10253 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
CASP3 P42574 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
RAB9A P51151 2/20 0.41
PKM P14618 3/20 0.41
PKLR P30613 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxycarbonyl Group SCHEMBL28072344 0.83 MEN1 (0.41) KMT2AMAPTMEN1CYP1A2CYP3A4
Ethoxycarbonyl Group SCHEMBL28829643 0.83 NQO2 (0.45) KMT2AMEN1PKMPKLR
Ethoxycarbonyl Group SCHEMBL28072423 0.83 NR4A2 (0.39) KMT2AMAPTMEN1L3MBTL1CYP1A2
Ethoxycarbonyl Group SCHEMBL27704233 0.83 ALDH1A1 (0.47) KMT2AMAPTMEN1NPC1GAA
SCHEMBL1849779 0.82 NPC1 (0.51) KMT2AMAPTMEN1NPC1GAA
Ethoxycarbonyl Group SCHEMBL27785547 0.79 PKM (0.55) KMT2AMAPTMEN1CYP1A2CYP3A4
Ethoxycarbonyl Group SCHEMBL27743421 0.79 ATM (0.62) KMT2AMAPTMEN1CYP1A2CYP3A4
Ethoxycarbonyl Group SCHEMBL27533058 0.77 CYP2A6 (0.44) KMT2AMAPTMEN1NPC1CYP1A2
Ethoxycarbonyl Group SCHEMBL27768618 0.77 CYP2A6 (0.44) KMT2AMAPTMEN1CYP1A2CYP3A4
Ethoxycarbonyl Group SCHEMBL27552104 0.77 CYP2A6 (0.44) KMT2AMAPTMEN1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105601555-A Method for preparing nitroindole derivatives UNIV SOOCHOW 2016-05-25 CN disclosed