SCHEMBL1849779

SCHEMBL1849779

O=[N+]([O-])c1c[nH]c2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.51
TDP1 Q9NUW8 3/20 0.51
MEN1 O00255 3/20 0.51
MAPT P10636 3/20 0.51
KMT2A Q03164 3/20 0.51
GAA P10253 2/20 0.51
CYP3A4 P08684 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
CASP3 P42574 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
PKM P14618 1/20 0.50
PKLR P30613 1/20 0.50
ALDH1A1 P00352 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7297581 0.87 NPC1 (0.48) NPC1TDP1MEN1MAPTKMT2A
Ethoxycarbonyl Group SCHEMBL28072241 0.82 KMT2A (0.43) NPC1TDP1MEN1MAPTKMT2A
SCHEMBL7912653 0.80 BCL2 (0.53) NPC1TDP1MEN1MAPTKMT2A
SCHEMBL15717048 0.78 ALDH1A1 (0.64) TDP1MEN1KMT2AALDH1A1KDM4E
SCHEMBL28967651 0.78 NR4A2 (0.49) NPC1TDP1MAPTPKMPKLR
SCHEMBL1802692 0.77 BCL2 (0.59) NPC1TDP1MEN1MAPTKMT2A
SCHEMBL15689980 0.76 ATM (0.41) NPC1TDP1MEN1MAPTKMT2A
SCHEMBL15689981 0.76 HPGD (0.46) NPC1TDP1MEN1MAPTKMT2A
SCHEMBL15689979 0.76 ATM (0.41) NPC1TDP1MEN1MAPTKMT2A
SCHEMBL6273670 0.76 GPR84 (0.68) NPC1MEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250043346-A1 SYSTEMS AND METHODS FOR DIFFERENTIALLY TAGGING NUCLEIC ACID MOLECULES 10X GENOMICS INC (US) 2025-02-06 US claimed
CN-118561851-A Preparation method of polysubstituted indolo [2,3-b ] carbazole compound 湖南师范大学 2024-08-30 CN claimed
CN-113666862-B Method for preparing chiral 3-nitroindole compounds through nickel-catalyzed asymmetric nitration reaction 山东大学 2024-05-31 CN claimed
CN-114524761-B Penta-cyclic indoline compound, preparation method and application thereof 成都大学 2023-11-14 CN claimed
CN-116621762-A 3-nitroindole analogue and preparation method thereof 川北医学院 2023-08-22 CN claimed
CN-115785110-A Indoline tetrahydropyrane compound, preparation method and application thereof 成都大学 2023-03-14 CN claimed
CN-115341017-A Kit and detection method for rapidly detecting gene variation based on lighted click connection probe 中国人民解放军陆军特色医学中心 2022-11-15 CN claimed
US-11371094-B2 Systems and methods for nucleic acid processing using degenerate nucleotides 10X GENOMICS, INC. (US) 2022-06-28 US claimed
CN-114524761-A Pentabenzocycloindoline compound, preparation method and application thereof 成都大学 2022-05-24 CN claimed
CN-108350499-B Convertible marking compositions, methods, and processes incorporating same 10X基因组学有限公司 2022-05-13 CN claimed
CN-114292277-A Indoline tetrahydropyrane compound and preparation method thereof 成都大学 2022-04-08 CN claimed
CN-113666862-A Method for preparing chiral 3-nitroindole compound by nickel-catalyzed asymmetric nitration reaction 山东大学 2021-11-19 CN claimed
US-20210285044-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID PROCESSING USING DEGENERATE NUCLEOTIDES 10X GENOMICS, INC. 2021-09-16 US claimed
EP-3377657-B1 TRANSFORMABLE TAGGING METHODS 10X GENOMICS INC (US) 2020-11-11 EP claimed
CN-109081807-B Method for preparing tri-substituted 4-aminocarbazole and di-substituted 1-aminodibenzo [ b, d ] thiophene compounds 台州学院 2020-08-04 CN claimed
CN-108947890-B Method for preparing disubstituted 4-aminocarbazole compound 台州学院 2020-08-04 CN claimed
CN-106399484-B Double-bubble fluorescent probe and application and kit thereof 中国人民解放军第三军医大学第一附属医院 2020-03-24 CN claimed
EP-3377657-A1 TRANSFORMABLE TAGGING COMPOSITIONS, METHODS, AND PROCESSES INCORPORATING SAME 10X Genomics, Inc. (US) 2018-09-26 EP claimed
US-20170145476-A1 TRANSFORMABLE TAGGING COMPOSITIONS, METHODS, AND PROCESSES INCORPORATING SAME 10X GENOMICS, INC. 2017-05-25 US claimed
EP-2035436-B1 FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS UCB PHARMA SA (BE) 2011-05-25 EP claimed