Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16072807 | 0.82 | CES2 (0.43) | NPC1RAB9ASMN1; SMN2PKMMEN1 | |
| SCHEMBL5217871 | 0.80 | CES2 (0.50) | NPC1RAB9ASMN1; SMN2PKMKMT2A | |
| SCHEMBL5217865 | 0.80 | CES2 (0.50) | NPC1RAB9ASMN1; SMN2PKMKMT2A | |
| SCHEMBL17426488 | 0.80 | CES2 (0.50) | NPC1RAB9ASMN1; SMN2PKMKMT2A | |
| SCHEMBL27816463 | 0.74 | CES2 (0.47) | NPC1RAB9ASMN1; SMN2PKMMEN1 | |
| SCHEMBL9706848 | 0.74 | CES2 (0.50) | NPC1RAB9ASMN1; SMN2PKMMEN1 | |
| SCHEMBL12180935 | 0.74 | CES2 (0.50) | NPC1RAB9ASMN1; SMN2PKMMEN1 | |
| SCHEMBL11543030 | 0.73 | CES2 (0.48) | NPC1RAB9ASMN1; SMN2PKMMEN1 | |
| SCHEMBL13983961 | 0.72 | CES2 (0.52) | NPC1RAB9ASMN1; SMN2PKMMEN1 | |
| SCHEMBL2812477 | 0.72 | CES2 (0.52) | NPC1RAB9ASMN1; SMN2PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456339-A | A kind of synthetic method of Cefuroxime Sodium | 湖北凌晟药业有限公司 | 2019-03-12 | — | — | CN | claimed |
| CN-105669700-A | Cefuroxime sodium new crystal type compound and preparation adopting particle process crystal product molecular assembly and form optimizing technology | 海南灵康制药有限公司 | 2016-06-15 | — | — | CN | claimed |
| CN-115353524-A | Synthesis method of cefuroxime sodium | 浙江东盈药业有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-109456339-A | A kind of synthetic method of Cefuroxime Sodium | 湖北凌晟药业有限公司 | 2019-03-12 | — | — | CN | disclosed |
| CN-109456339-A | A kind of synthetic method of Cefuroxime Sodium | 湖北凌晟药业有限公司 | 2019-03-12 | — | — | CN | disclosed |