Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5217871 | 1.00 | CES2 (0.50) | CES2CES1KMT2AMAOBRAB9A | |
| SCHEMBL17426488 | 1.00 | CES2 (0.50) | CES2CES1KMT2AMAOBRAB9A | |
| SCHEMBL27816463 | 0.87 | CES2 (0.47) | CES2CES1KMT2AMAOBRAB9A | |
| SCHEMBL16072807 | 0.86 | CES2 (0.43) | CES2CES1KMT2AMAOBRAB9A | |
| SCHEMBL5185688 | 0.85 | CES2 (0.52) | CES2CES1KMT2AMAOBRAB9A | |
| SCHEMBL2812477 | 0.85 | CES2 (0.52) | CES2CES1KMT2AMAOBRAB9A | |
| SCHEMBL8170511 | 0.85 | CES2 (0.52) | CES2CES1KMT2AMAOBRAB9A | |
| SCHEMBL20863020 | 0.85 | CES2 (0.52) | CES2CES1KMT2AMAOBRAB9A | |
| SCHEMBL13983961 | 0.85 | CES2 (0.52) | CES2CES1KMT2AMAOBRAB9A | |
| SCHEMBL11457463 | 0.85 | CES2 (0.52) | CES2CES1KMT2AMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166928-B1 | PROCESS FOR THE PREPARATION OF 3-HYDROXYPICOLINIC ACIDS | DOW AGROSCIENCES LLC (US) | 2019-04-03 | — | — | EP | disclosed |
| EP-3166928-A1 | PROCESS FOR THE PREPARATION OF 3-HYDROXYPICOLINIC ACIDS | Dow AgroSciences LLC (US) | 2017-05-17 | — | — | EP | disclosed |
| US-9353060-B2 | Process for the preparation of 3-hydroxypicolinic acids | DOW AGROSCIENCES LLC (US) | 2016-05-31 | — | — | US | disclosed |
| US-9353060-B2 | Process for the preparation of 3-hydroxypicolinic acids | DOW AGROSCIENCES LLC (US) | 2016-05-31 | — | — | US | disclosed |
| US-20160009647-A1 | PROCESS FOR THE PREPARATION OF 3-HYDROXYPICOLINIC ACIDS | CORTEVA AGRISCIENCE LLC | 2016-01-14 | — | — | US | disclosed |
| US-20160009647-A1 | PROCESS FOR THE PREPARATION OF 3-HYDROXYPICOLINIC ACIDS | CORTEVA AGRISCIENCE LLC | 2016-01-14 | — | — | US | disclosed |
| WO-2016007532-A1 | PROCESS FOR THE PREPARATION OF 3-HYDROXYPICOLINIC ACIDS | DOW AGROSCIENCES LLC (US) | 2016-01-14 | — | — | WO | disclosed |
| WO-2016007532-A1 | PROCESS FOR THE PREPARATION OF 3-HYDROXYPICOLINIC ACIDS | DOW AGROSCIENCES LLC (US) | 2016-01-14 | — | — | WO | disclosed |
| US-20070275954-A1 | Novel Fused Heterocycles and Uses Thereof | ASTRAZENECA AB (SE) | 2007-11-29 | — | — | US | disclosed |
| EP-1751119-A1 | NOVEL FUSED HETEROCYCLES AND USES THEREOF | AstraZeneca AB (SE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005111001-A1 | NOVEL FUSED HETEROCYCLES AND USES THEREOF | ASTRAZENECA AB (SE) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275954-A1 | Novel Fused Heterocycles and Uses Thereof | VIP, CCKBR, HRH2 | CES2 1687/4885CES1 1016/4885KMT2A 3978/4885 |
| US-20160009647-A1 | PROCESS FOR THE PREPARATION OF 3-HYDROXYPICOLINIC ACIDS | HPD, HAAO, CYP4A11 | CES2 1324/4885CES1 1840/4885KMT2A 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.