Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457463 | 1.00 | CES2 (0.52) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL4609969 | 1.00 | CES2 (0.52) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| Ammonia Solution, Strong SCHEMBL4752940 | 0.98 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| Ammonia Solution, Strong SCHEMBL5211578 | 0.98 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| Ammonia Solution, Strong SCHEMBL28417876 | 0.98 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL13983961 | 0.86 | CES2 (0.52) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL5217865 | 0.85 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL12180935 | 0.85 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL9634783 | 0.85 | CES2 (0.55) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL17426488 | 0.85 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025299-A | Synthesis method of (Z) -2-methoxyimino-2-furyl ammonium acetate | 河南立诺制药有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-118561788-A | Methoxyiminofuran acetic acid cis-trans isomerism conversion method | 河南立诺制药有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-113999194-B | Process for the preparation of furan ammonium salts | 山东金城医药化工有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-113999194-A | Process for the preparation of furan ammonium salts | 山东金城医药化工有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-111440196-A | Method for nickel-based catalytic synthesis of 3-decarbamoyl cefuroxime acid | 山东金城柯瑞化学有限公司 | 2020-07-24 | — | — | CN | claimed |
| CN-102070572-B | Method for recovering and preparing furanone acid from syn-2-methoxyimino-2-(2-furayl)-acetic acid-ammonia salt waste residue | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL CO LTD | 2012-10-03 | — | — | CN | claimed |
| CN-102070572-A | Method for recovering and preparing furanone acid from syn-2-methoxyimino-2-(2-furayl)-acetic acid-ammonia salt waste residue | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL CO LTD | 2011-05-25 | — | — | CN | claimed |
| EP-1319009-B1 | INTERMEDIATES IN CEPHALOSPORIN PRODUCTION | SANDOZ AG (CH) | 2008-10-22 | — | — | EP | claimed |
| US-6894162-B2 | Intermediates in cephalosporin production | SANDOZ GMBH (AT) | 2005-05-17 | — | — | US | claimed |
| CN-1200941-C | Intermediates in cephalosporing production | BIOCHEMIE GMBH (AT) | 2005-05-11 | — | — | CN | claimed |
| WO-2004050663-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFUROXIME SODIUM | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2004-06-17 | — | — | WO | claimed |
| WO-2004041831-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFUROXIME SODIUM | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-05-21 | — | — | WO | claimed |
| US-20040092735-A1 | Process for the preparation of cefuroxime sodium | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-05-13 | — | — | US | claimed |
| CN-1454212-A | Intermediates in cephalosporing production | BIOCHEMIE GMBH (AT) | 2003-11-05 | — | — | CN | claimed |
| US-20030171577-A1 | Intermediates in cephalosporin production | SANDOZ GMBH (FORMERLY BIOCHEMIE GMBH) (AT) | 2003-09-11 | — | — | US | claimed |
| EP-1319009-A1 | INTERMEDIATES IN CEPHALOSPORIN PRODUCTION | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2003-06-18 | — | — | EP | claimed |
| WO-2002020532-A1 | INTERMEDIATES IN CEPHALOSPORIN PRODUCTION | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2002-03-14 | — | — | WO | claimed |
| US-4876351-A | Process for the separation of a mixture of \"syn\" and \"anti\" oxime isomers | GLAXO GROUP LIMITED (GB) | 1989-10-24 | — | — | US | claimed |
| JP-56133293-A | — | — | None | — | — | JP | disclosed |
| US-4103085-A | CEPHALOSPORIN ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092735-A1 | Process for the preparation of cefuroxime sodium | CYP2F1, CYP51A1, CYP17A1 | CES2 1088/4885CES1 113/4885PTPN1 1363/4885 |
| US-20030171577-A1 | Intermediates in cephalosporin production | BBOX1, SLC6A12, BCHE | CES2 55/4885CES1 665/4885PTPN1 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.