Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.56 |
| ▸ | ERN1 | O75460 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 5/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677328 | 0.90 | APP (0.81) | APPCA1CA2CA9HSD17B1 | |
| SCHEMBL27159530 | 0.90 | APP (0.81) | APPCA1CA2CA9HSD17B1 | |
| SCHEMBL9602374 | 0.85 | HSD17B1 (0.61) | APPCA1CA2CA9HSD17B1 | |
| SCHEMBL23555697 | 0.84 | APP (0.72) | APPCA1CA2CA9HSD17B1 | |
| SCHEMBL5768436 | 0.84 | APP (0.72) | APPCA1CA2CA9HSD17B1 | |
| SCHEMBL29766071 | 0.84 | APP (0.71) | APPCA1CA2CA9HSD17B1 | |
| SCHEMBL163523 | 0.84 | APP (0.71) | APPCA1CA2CA9HSD17B1 | |
| Bromide SCHEMBL31564934 | 0.82 | APP (0.69) | APPCA1CA2CA9HSD17B1 | |
| SCHEMBL10300223 | 0.82 | ESR1 (0.50) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL27631114 | 0.82 | HSD17B1 (0.77) | APPCA1CA2CA9HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110791775-B | Method for continuously preparing 2-aryl-benzothiophene/furan compounds by using electrochemical microchannel reaction device | 南京工业大学 | 2021-02-05 | — | — | CN | disclosed |
| CN-110483475-B | Method for preparing benzothiophene compound by silver oxide catalysis method | 绍兴文理学院 | 2020-11-27 | — | — | CN | disclosed |
| CN-110791775-A | Method for continuously preparing 2-aryl-benzothiophene/furan compounds by using electrochemical microchannel reaction device | 南京工业大学 | 2020-02-14 | — | — | CN | disclosed |
| CN-110483475-A | A kind of method that silver oxide catalysis method prepares benzothiophenes | UNIV SHAOXING | 2019-11-22 | — | — | CN | disclosed |
| CN-103724319-B | The preparation method of a kind of benzothiophenes and purification method thereof | 温州大学 | 2016-06-29 | — | — | CN | disclosed |