Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13825168 | 0.81 | TDP1 (0.46) | TDP1ATMPDGFRBPDGFRAMAPT | |
| SCHEMBL1582196 | 0.81 | MAP4K4 (0.49) | TDP1ATMPDGFRBPDGFRAMAPT | |
| SCHEMBL12528627 | 0.80 | TDP1 (0.41) | TDP1ATMMAPTALDH1A1LMNA | |
| SCHEMBL13824897 | 0.78 | TDP1 (0.42) | TDP1ATMPDGFRBPDGFRAMAPT | |
| SCHEMBL27686103 | 0.77 | ERN1 (0.44) | TDP1ATMPDGFRBPDGFRAMAPT | |
| SCHEMBL20364812 | 0.77 | ALDH1A1 (0.53) | TDP1ATMMAPTALDH1A1LMNA | |
| SCHEMBL28736511 | 0.76 | MAP4K4 (0.40) | TDP1ATMPDGFRBPDGFRAMAPT | |
| SCHEMBL27686102 | 0.76 | MAPT (0.39) | TDP1ATMPDGFRBPDGFRAMAPT | |
| SCHEMBL20242084 | 0.76 | ERN1 (0.49) | TDP1PDGFRBPDGFRAMAPTALDH1A1 | |
| SCHEMBL18376431 | 0.75 | MAPT (0.45) | TDP1ATMPDGFRBPDGFRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103396359-B | Iminipyridine derivatives and they purposes as microbicide | 先正达参股股份有限公司 | 2016-06-29 | — | — | CN | disclosed |