Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736511 | 0.87 | MAP4K4 (0.40) | MAPTALDH1A1PDGFRBPDGFRAGAA | |
| SCHEMBL27667112 | 0.79 | MAPT (0.47) | MAPTPDGFRBPDGFRACHRNA7GRIN2B | |
| SCHEMBL27686103 | 0.78 | ERN1 (0.44) | MAPTALDH1A1PDGFRBPDGFRAGAA | |
| SCHEMBL28073068 | 0.76 | TDP1 (0.46) | MAPTALDH1A1PDGFRBPDGFRAGAA | |
| SCHEMBL27686153 | 0.76 | CHRNA7 (0.47) | PDGFRBPDGFRACHRNA7GRIN2BGRIN1 | |
| SCHEMBL16322862 | 0.75 | MAPT (0.39) | MAPTALDH1A1RAB9A | |
| SCHEMBL5504097 | 0.75 | ALDH1A1 (0.43) | MAPTALDH1A1GAATDP1TTR | |
| SCHEMBL13825168 | 0.74 | TDP1 (0.46) | MAPTALDH1A1PDGFRBPDGFRAGAA | |
| SCHEMBL1582196 | 0.74 | MAP4K4 (0.49) | MAPTALDH1A1PDGFRBPDGFRAGAA | |
| SCHEMBL27667089 | 0.72 | CYP4F2 (0.38) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1976915-A | HIV integrase inhibitors | SMITHKLINE BEECHAM CORP (US) | 2007-06-06 | — | — | CN | disclosed |