Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584199 | 0.81 | LMNA (0.44) | MAPTPOLBMAPK1ALDH1A1NPC1 | |
| SCHEMBL5195057 | 0.80 | SLC6A4 (0.49) | ERN1PDGFRBPDGFRAALDH1A1SLC6A4 | |
| SCHEMBL27667113 | 0.80 | IKBKB (0.50) | EGLN1PDGFRBPDGFRAGRIN2BMAPT | |
| SCHEMBL27686155 | 0.78 | CHRNA7 (0.46) | EGLN1PDGFRBPDGFRAGRIN2BSLC6A4 | |
| SCHEMBL27686102 | 0.78 | MAPT (0.39) | ERN1PDGFRBPDGFRAGRIN2BMAPT | |
| SCHEMBL28073068 | 0.77 | TDP1 (0.46) | ERN1PDGFRBPDGFRAGRIN2BMAPT | |
| SCHEMBL23484278 | 0.76 | CHRNA7 (0.49) | EGLN1PDGFRBPDGFRAGRIN2BMAPT | |
| SCHEMBL11377331 | 0.76 | MAPK1 (0.59) | MAPTPOLBMAPK1ALDH1A1ATM | |
| SCHEMBL23537652 | 0.76 | SMN1; SMN2 (0.48) | PDGFRBPDGFRAMAPTPOLBMAPK1 | |
| SCHEMBL28736511 | 0.75 | MAP4K4 (0.40) | ERN1EGLN1PDGFRBPDGFRAGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1976915-A | HIV integrase inhibitors | SMITHKLINE BEECHAM CORP (US) | 2007-06-06 | — | — | CN | disclosed |