Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | QDPR | P09417 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481571 | 0.87 | — | — | |
| SCHEMBL1815764 | 0.75 | HTR2C (0.58) | HTR2CSLC18A3SIGMAR1ADRB2SLC6A2 | |
| SCHEMBL3553262 | 0.73 | HTR2C (0.60) | HTR2CSLC18A3SIGMAR1ADRB2SLC6A2 | |
| SCHEMBL29922358 | 0.73 | HTR2C (0.60) | HTR2CSLC18A3SIGMAR1ADRB2SLC6A2 | |
| SCHEMBL27964417 | 0.71 | HTR2C (0.61) | HTR2CSLC18A3SIGMAR1ADRB2SLC6A2 | |
| SCHEMBL4830015 | 0.70 | GABRA1 (0.49) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL188584 | 0.69 | SLC18A3 (0.61) | HTR2CSLC18A3SIGMAR1QDPR | |
| SCHEMBL28061550 | 0.68 | HTR2C (0.42) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL7398897 | 0.68 | TDO2 (0.39) | — | |
| SCHEMBL2092662 | 0.68 | SLC18A3 (0.61) | HTR2CSLC18A3SIGMAR1QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105705488-A | Acetylcholinesterase inhibitor compounds and 5HT4 serotonergic receptor agonisis, with promnesia effect, methods for the preparation thereof and pharmaceutical compositions containing same | 卡昂大学 | 2016-06-22 | — | — | CN | disclosed |