Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.41 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4940492 | 0.85 | EPAS1 (0.56) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL30615510 | 0.85 | EPAS1 (0.56) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL3571014 | 0.82 | MAPK1 (0.62) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL22583718 | 0.82 | MAPK1 (0.51) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL4379830 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL16634860 | 0.79 | HCAR3 (0.63) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL16634858 | 0.79 | HCAR3 (0.63) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL397773 | 0.79 | MAPK1 (0.77) | MAPK1L3MBTL1TDP1ALDH1A1CASP7 | |
| SCHEMBL3691221 | 0.77 | MAP2K1 (0.48) | MAP2K1MAP2K2 | |
| SCHEMBL390986 | 0.77 | MAP2K1 (0.58) | MAPK1MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103479604-B | N-(virtue amino) sulfamide derivative including polymorph and compositions, its using method and preparation method as mek inhibitor | 阿迪生物科学公司 | 2016-08-10 | — | — | CN | disclosed |