Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 6/20 | 0.44 |
| ▸ | CES2 | O00748 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAM | P19021 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388453 | 0.92 | LMNA (0.61) | LMNACES1CES2ALDH1A1MAPT | |
| SCHEMBL2116775 | 0.83 | LMNA (0.53) | LMNACES1CES2ALDH1A1MAPT | |
| SCHEMBL28035203 | 0.81 | ALDH1A1 (0.35) | LMNAALDH1A1TSHRTDP1 | |
| SCHEMBL242588 | 0.78 | ALDH1A1 (0.68) | LMNACES1CES2ALDH1A1MAPT | |
| SCHEMBL7291698 | 0.78 | LMNA (0.62) | LMNAALDH1A1MAPTDGKAMAPK1 | |
| SCHEMBL8886262 | 0.77 | LMNA (0.47) | LMNACES1ALDH1A1MAPTDGKA | |
| SCHEMBL6061322 | 0.76 | CES1 (0.62) | LMNACES1CES2ALDH1A1TP53 | |
| SCHEMBL10908594 | 0.76 | LMNA (0.66) | LMNAALDH1A1MAPTDGKAMAPK1 | |
| SCHEMBL10903688 | 0.76 | LMNA (0.66) | LMNAALDH1A1MAPTDGKAMAPK1 | |
| SCHEMBL29069454 | 0.76 | LMNA (0.66) | LMNAALDH1A1MAPTDGKAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334729-B | Autologous inducible expression, and utilizing enterobacteriaceae lactobacteriaceae to produce the purposes in useful metabolin | 味之素株式会社 | 2016-06-29 | — | — | CN | disclosed |