Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462514 | 0.81 | TSHR (0.38) | ALDH1A1TSHR | |
| SCHEMBL28073289 | 0.81 | LMNA (0.50) | ALDH1A1LMNATSHRTDP1 | |
| SCHEMBL386957 | 0.79 | NAAA (0.39) | ALDH1A1LMNANAAAALOX15TSHR | |
| SCHEMBL28285055 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNANAAAALOX15TSHR | |
| SCHEMBL4388453 | 0.78 | LMNA (0.61) | ALDH1A1LMNATSHR | |
| SCHEMBL5706390 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNANAAAALOX15TSHR | |
| SCHEMBL5706391 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNANAAAALOX15TSHR | |
| SCHEMBL2012306 | 0.76 | TSHR (0.35) | TSHR | |
| Ammonia Solution, Strong SCHEMBL28098443 | 0.75 | ALDH1A1 (0.43) | ALDH1A1LMNANAAAALOX15TSHR | |
| SCHEMBL10700496 | 0.75 | NAAA (0.37) | ALDH1A1LMNANAAAALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111084-A | Synthesis method of 4-substituted-3-methyl-2,4-dioxobutyrate | UNIV TAIZHOU | 2015-12-02 | — | — | CN | disclosed |