Nitrobenzene

Nitrobenzene

SCHEMBL28073307

O=[N+]([O-])c1ccccc1.c1cc[nH]c1.c1ccncc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
LMNA P02545 2/20 0.57
POLB P06746 2/20 0.47
MAPT P10636 5/20 0.43
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
L3MBTL1 Q9Y468 3/20 0.42
CYP19A1 P11511 1/20 0.42
MEN1 O00255 1/20 0.42
CRHBP P24387 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
CRHR2 Q13324 1/20 0.42
TLR9 Q9NR96 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrobenzene SCHEMBL3237422 0.89 ALDH1A1 (0.73) ALDH1A1LMNAPOLBMAPTRAB9A
Nitrobenzene SCHEMBL27527397 0.89 ALDH1A1 (0.73) ALDH1A1LMNAPOLBL3MBTL1MEN1
Pyrrole SCHEMBL27708626 0.80 ALDH1A1 (0.56) ALDH1A1LMNAMAPTL3MBTL1MEN1
Pyridine SCHEMBL28185807 0.79 TSHR (0.39) TSHR
Pyridine SCHEMBL28328352 0.79 LMNA (0.42) ALDH1A1LMNAPOLBMAPTRAB9A
Nitrobenzene SCHEMBL9274922 0.79 ALDH1A1 (0.57) ALDH1A1LMNAPOLBMAPTRAB9A
Dinitrophenylene SCHEMBL28214822 0.77 TSHR (0.71) ALDH1A1LMNAMAPTRAB9ANPC1
Nitrobenzene SCHEMBL897631 0.76 ALDH1A1 (0.89) ALDH1A1LMNAPOLBL3MBTL1MEN1
Nitrobenzene SCHEMBL11050641 0.76 ALDH1A1 (0.89) ALDH1A1LMNAPOLBL3MBTL1MEN1
Nitrobenzene SCHEMBL11144731 0.76 ALDH1A1 (0.89) ALDH1A1LMNAPOLBL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108450567-A A kind of preparation method of preventing hypertension tea oil 管天球 2018-08-28 CN disclosed
CN-106362156-A Saccharide micro-particle carrier, preparation method, use method, and application thereof 谭淞文 2017-02-01 CN disclosed
CN-103432133-B The purposes of nuclear receptor binding agents GTX公司 2016-08-10 CN disclosed