Pyridine

Pyridine

SCHEMBL28328352

O=[N+]([O-])c1cc[nH]c1.c1ccncc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 5/20 0.40
RAB9A P51151 3/20 0.40
NPC1 O15118 2/20 0.40
POLB P06746 2/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
HTT P42858 1/20 0.37
TSHR P16473 1/20 0.36
HPGD P15428 2/20 0.36
CHRNB2 P17787 1/20 0.35
CHRNA5 P30532 1/20 0.35
CHRNA4 P43681 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MEN1 O00255 1/20 0.34
CRHBP P24387 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
CRHR2 Q13324 1/20 0.34
TLR9 Q9NR96 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28818 0.84
Water SCHEMBL28124895 0.82
Nitrobenzene SCHEMBL28073307 0.79 ALDH1A1 (0.57) LMNAALDH1A1MAPTRAB9ANPC1
Nitrobenzene SCHEMBL3237422 0.77 ALDH1A1 (0.73) LMNAALDH1A1MAPTRAB9ANPC1
SCHEMBL28145654 0.76 KDM4E (0.49) LMNAALDH1A1MAPTPOLBHTT
SCHEMBL21359713 0.74 ALDH1A1 (0.38) LMNAALDH1A1TSHRMEN1KMT2A
Pyridine SCHEMBL28276898 0.73 GAA (0.39) ALDH1A1MAPTL3MBTL1HTTTSHR
Dinitrophenylene SCHEMBL28214822 0.73 TSHR (0.71) LMNAALDH1A1MAPTRAB9ANPC1
Phosphoramidic Acid SCHEMBL311554 0.73 CA1 (0.41) LMNAALDH1A1TSHR
Dinitrophenylene SCHEMBL2428435 0.72 TSHR (0.68) LMNAALDH1A1MAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106890671-A A kind of catalyst for producing methyl acetate, its preparation method and application 中国科学院大连化学物理研究所 2017-06-27 CN claimed
CN-106890668-A A kind of catalyst for producing methyl acetate, its preparation method and application 中国科学院大连化学物理研究所 2017-06-27 CN claimed
CN-110446950-A structure and optical sensor FUJIFILM CORP 2019-11-12 CN disclosed
CN-110330465-A Hydrazone amide derivatives and its application in preparation prevention and treatment alopecia agent 深圳市三启药物开发有限公司 2019-10-15 CN disclosed
CN-110229118-A Hydrazone amide derivatives and its preparing the application in osteosporosis resistant medicament 深圳市三启药物开发有限公司 2019-09-13 CN disclosed
CN-109790390-A Dispersion liquid, composition, film, the manufacturing method of film and dispersing agent 富士胶片株式会社 2019-05-21 CN disclosed
CN-109415599-A Alternative oxidizing agents for cobalt chemical mechanical polishing 嘉柏微电子材料股份公司 2019-03-01 CN disclosed
CN-104334546-B Novel ring-substituted N-pyridyl amides as kinase inhibitors 诺华股份有限公司 2017-05-03 CN disclosed