Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397928 | 0.78 | KMT2A (0.59) | MAPTALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL28073890 | 0.77 | HSD17B2 (0.52) | GABRA1GABRB2ADORA3ADORA2AADORA1 | |
| SCHEMBL15885670 | 0.77 | KEAP1 (0.64) | MAPTALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL28073904 | 0.76 | HRH3 (0.48) | KEAP1LTA4H | |
| SCHEMBL28138784 | 0.75 | NPC1 (0.49) | MAPTALDH1A1POLBHPGDKEAP1 | |
| SCHEMBL27568071 | 0.72 | SCN4A (0.61) | LTA4HNPC1RAB9AKMT2A | |
| SCHEMBL27939128 | 0.71 | ATM (0.37) | KEAP1MKNK1MKNK2KMT2A | |
| SCHEMBL21051373 | 0.71 | ACSS2 (0.43) | MAPTALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL21051521 | 0.71 | DYRK1A (0.44) | MAPTALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL28073873 | 0.69 | CA2 (0.44) | MAPTALDH1A1HPGDHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980222-B | A kind of 2-amino-5-replaces-1,3,4-diazole and its preparation method and application | 陕西科技大学 | 2016-08-17 | — | — | CN | disclosed |