Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27938698 | 0.98 | — | — | |
| SCHEMBL467340 | 0.77 | — | — | |
| SCHEMBL27834453 | 0.76 | CYP2D6 (0.38) | LMNAMAPTSLC6A2SLC6A4BLM | |
| SCHEMBL21408121 | 0.74 | ALDH1A1 (0.32) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL7783653 | 0.72 | — | — | |
| SCHEMBL27540254 | 0.70 | — | — | |
| SCHEMBL14679145 | 0.70 | — | — | |
| SCHEMBL25748 | 0.69 | — | — | |
| SCHEMBL5706554 | 0.69 | GRM8 (0.37) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL27404442 | 0.68 | CASP1 (0.34) | ALDH1A1LMNAMAPTPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105689000-B | A kind of tetraamido macrocyclic ligand catalyst and preparation method thereof | 魏东初 | 2018-05-08 | — | — | CN | disclosed |
| CN-105689000-A | Novel tetra-amido macrocyclic ligand catalyst and preparing method thereof | 魏东初 | 2016-06-22 | — | — | CN | disclosed |
| CN-105689000-A | Novel tetra-amido macrocyclic ligand catalyst and preparing method thereof | 魏东初 | 2016-06-22 | — | — | CN | disclosed |