SCHEMBL5706554

SCHEMBL5706554

NC(NCC(=O)O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.37
GRM6 O15303 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GSR P00390 1/20 0.37
CYP1A2 P05177 1/20 0.37
GRIK1 P39086 1/20 0.37
GRM5 P41594 1/20 0.37
GRIA1 P42261 1/20 0.37
GRIA2 P42262 1/20 0.37
GRIA3 P42263 1/20 0.37
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
SLC1A1 P43005 1/20 0.37
GRIA4 P48058 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIK2 Q13002 1/20 0.37
GRIK3 Q13003 1/20 0.37
GRIN2B Q13224 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1741229 0.80 CTH (0.38) GRIK1TDP1ALDH1A1LMNAMAPT
SCHEMBL7783653 0.78
SCHEMBL1263396 0.74
SCHEMBL25748 0.74
SCHEMBL28963615 0.73 USP2 (0.39) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL3179343 0.72 LDHA (0.37) TDP1ALDH1A1LMNAMAPTPTGS2
SCHEMBL27422304 0.72 GAA (0.46) CYP1A2ALDH1A1
SCHEMBL16005555 0.72
SCHEMBL8828900 0.72
Hydrochloric Acid SCHEMBL1728563 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295632-A1 METHODS OF CONTROLLING RED BLOOD CELL PRODUCTION WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-09-21 US claimed
US-20190270992-A1 METHODS OF CONTROLLING RED BLOOD CELL PRODUCTION WISCONSIN ALUMNI RESEARCH FOUNDATION 2019-09-05 US claimed
US-20230295632-A1 METHODS OF CONTROLLING RED BLOOD CELL PRODUCTION WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-09-21 US disclosed
US-20190270992-A1 METHODS OF CONTROLLING RED BLOOD CELL PRODUCTION WISCONSIN ALUMNI RESEARCH FOUNDATION 2019-09-05 US disclosed
EP-1348024-B1 DESIGN AND USE OF ADVANCED ZINC CHELATING PEPTIDES TO REGULATE MATRIX METALLOPROTEINASES KIMBERLY CLARK CO (US) 2006-10-11 EP disclosed
US-7041787-B2 Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases KIMBERLY-CLARK WORLDWIDE, INC. (US) 2006-05-09 US disclosed
EP-1348024-A2 DESIGN AND USE OF ADVANCED ZINC CHELATING PEPTIDES TO REGULATE MATRIX METALLOPROTEINASES KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-10-01 EP disclosed
US-20030073808-A1 Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases AVENT, INC. 2003-04-17 US disclosed
WO-2002053173-A2 DESIGN AND USE OF ADVANCED ZINC CHELATING PEPTIDES TO REGULATE MATRIX METALLOPROTEINASES KIMBERLY-CLARK WORLDWIDE, INC. (US) 2002-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073808-A1 Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases TIMP3, MMP12, MMP16 GRM8 3996/4885GRM6 3390/4885GRIN2D 4537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.