Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31381950 | 0.85 | AURKA (0.41) | HTR2AHTR2CAURKAKDRAURKB | |
| SCHEMBL17813878 | 0.81 | HTR2A (0.42) | HTR2AHTR2CAURKAKDRAURKB | |
| SCHEMBL29878050 | 0.78 | HTR2A (0.40) | HTR2AHTR2CAURKAKDRAURKB | |
| SCHEMBL19366817 | 0.76 | HTR2A (0.39) | HTR2AHTR2CAURKAKDRAURKB | |
| SCHEMBL17808241 | 0.76 | HTR2A (0.39) | HTR2AHTR2CAURKAKDRAURKB | |
| SCHEMBL2355586 | 0.76 | ASPH (0.38) | PIK3R1PIK3CA | |
| SCHEMBL29091803 | 0.76 | AKR1C3 (0.34) | PIK3R1PIK3CALRRK2MAPTAAK1 | |
| SCHEMBL23912507 | 0.76 | ALDH1A1 (0.47) | AURKADHFRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3840400 | 0.76 | PIK3R1 (0.42) | PIK3R1PIK3CAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15005974 | 0.75 | ALDH1A1 (0.39) | HTR2AHTR2CDHFRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452218-A | Pyridinylimidazoles ketone as herbicide | SYNGENTA PARTICIPATIONS AG | 2019-11-15 | — | — | CN | disclosed |
| CN-105658637-A | Pyridylimidazolones as herbicides | 先正达参股股份有限公司 | 2016-06-08 | — | — | CN | disclosed |