Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | JUN | P05412 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28074115 | 0.76 | HTR2A (0.40) | PIK3R1PIK3CA | |
| SCHEMBL1536029 | 0.75 | ASPH (0.53) | ASPHKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL5216501 | 0.74 | ASPH (0.36) | ASPHRXRARXRBRXRG | |
| Hydrochloric Acid SCHEMBL20605153 | 0.73 | ASPH (0.51) | ASPHKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL1929528 | 0.73 | ASPH (0.42) | ASPHKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL29411280 | 0.71 | ASPH (0.67) | ASPHKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL474036 | 0.71 | ASPH (0.67) | ASPHKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL3128651 | 0.71 | L3MBTL1 (0.39) | ASPHMRGPRX4 | |
| SCHEMBL3129046 | 0.71 | XPO1 (0.48) | JUNNFKB1NFKB2RELA | |
| SCHEMBL29091803 | 0.71 | AKR1C3 (0.34) | MRGPRX4AKR1C3AKR1C2PIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352723-B1 | PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS | BAYER IP GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-2352723-A2 | HALOGEN-SUBSTITUTED COMPOUNDS USED AS PESTICIDES | Bayer CropScience AG (DE) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010051926-A2 | NEW HALOGEN-SUBSTITUTED BONDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-05-14 | — | — | WO | disclosed |
| EP-2184273-A1 | Halogen substituted compounds as pesticides | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |