Toluene

Toluene

SCHEMBL28074309

CCCCOC(=O)CCCCC(=O)OCCCC.Cc1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.55
TSHR P16473 4/20 0.53
TDP1 Q9NUW8 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
LTA4H P09960 2/20 0.49
ALDH1A1 P00352 4/20 0.48
GAA P10253 1/20 0.48
CYP3A4 P08684 2/20 0.48
MAPK1 P28482 2/20 0.48
CYP4F2 P78329 1/20 0.48
CYP4A11 Q02928 1/20 0.48
TP53 P04637 1/20 0.47
EPHX2 P34913 1/20 0.47
HSD17B10 Q99714 1/20 0.46
DNM1 Q05193 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL28574254 0.97 TSHR (0.53) DGKATSHRTDP1L3MBTL1MEN1
Toluene SCHEMBL28296748 0.94 DGKA (0.61) DGKATSHRALDH1A1CYP3A4MAPK1
Toluene SCHEMBL28304376 0.94 DGKA (0.61) DGKATSHRALDH1A1CYP3A4MAPK1
Toluene SCHEMBL10334155 0.93 DGKA (0.51) DGKATSHRTDP1L3MBTL1MEN1
Toluene SCHEMBL28874682 0.89 DGKA (0.44) DGKATSHRTDP1L3MBTL1MEN1
Toluene SCHEMBL9711835 0.88 NAAA (0.56) TSHRTDP1L3MBTL1MEN1KMT2A
Toluene SCHEMBL4749551 0.87 CYP4F2 (0.55) DGKATSHRALDH1A1CYP4F2CYP4A11
Toluene SCHEMBL28845143 0.87 CYP4F2 (0.55) DGKALTA4HALDH1A1GAACYP4F2
Toluene SCHEMBL6270207 0.87 CYP4F2 (0.55) DGKATSHRALDH1A1CYP4F2CYP4A11
Toluene SCHEMBL28150255 0.87 CYP4F2 (0.55) DGKALTA4HALDH1A1GAACYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105820308-A Preparation method and application of moisture reaction type polyurethane hot-melt adhesive for composite floor 高鼎精细化工(昆山)有限公司 2016-08-03 CN claimed