Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9898935 | 0.84 | P2RX7 (0.34) | CTSKP2RX7CTSLMEN1MAPK1 | |
| SCHEMBL6703818 | 0.81 | P2RX7 (0.35) | CTSKP2RX7CTSLMEN1MAPK1 | |
| SCHEMBL17606749 | 0.81 | TDP1 (0.36) | CTSKP2RX7CTSLMEN1MAPK1 | |
| SCHEMBL22015821 | 0.80 | APLNR (0.36) | CTSKP2RX7CTSLMEN1MAPK1 | |
| SCHEMBL23538650 | 0.78 | P2RX7 (0.34) | CTSKP2RX7CTSLMEN1MAPK1 | |
| SCHEMBL23538780 | 0.78 | P2RX7 (0.34) | CTSKP2RX7CTSLMEN1MAPK1 | |
| SCHEMBL14814146 | 0.78 | CA1 (0.35) | CTSKP2RX7CTSLMEN1MAPK1 | |
| Acetic Acid SCHEMBL28797854 | 0.77 | P2RX7 (0.34) | CTSKP2RX7CTSLMEN1MAPK1 | |
| SCHEMBL23276791 | 0.76 | CTSL (0.39) | CTSKP2RX7CTSL | |
| SCHEMBL9175696 | 0.76 | P2RX7 (0.33) | P2RX7CTSLMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-105611923-B | Sodium channel modulators for the treatment of pain and diabetes | 卓莫赛尔公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-104619709-B | Imidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105611923-A | Sodium channel modulators for the treatment of pain and diabetes | CHROMOCELL CORP | 2016-05-25 | — | — | CN | disclosed |