Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 8/20 | 0.43 |
| ▸ | ABL1 | P00519 | 6/20 | 0.43 |
| ▸ | BCR | P11274 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1202858 | 0.75 | RAB9A (0.36) | KDM4ENPC1ALDH1A1RAB9ACYP1A2 | |
| SCHEMBL5538279 | 0.74 | KDM4E (0.48) | SCN5AABL1BCRKDM4ENPC1 | |
| SCHEMBL29519754 | 0.73 | CYP2D6 (0.55) | SCN5AABL1BCRKDM4ENPC1 | |
| SCHEMBL17973845 | 0.71 | ABL1 (0.56) | ABL1BCRKDM4EGAAMAPT | |
| SCHEMBL1229053 | 0.71 | ABL1 (0.52) | SCN5AABL1BCRKDM4EMAPT | |
| SCHEMBL13721022 | 0.70 | — | — | |
| SCHEMBL5924062 | 0.70 | LMNA (0.40) | ABL1BCRKDM4ENPC1MAPT | |
| SCHEMBL5537569 | 0.69 | SCN5A (0.44) | SCN5AKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL1723225 | 0.69 | KDM4E (0.43) | SCN5AABL1BCRKDM4ENPC1 | |
| SCHEMBL16635303 | 0.69 | KMO (0.54) | SCN5AABL1BCRKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612153-A | Substituted sulfonamide compounds as TRPA1 conditioner | HOFFMANN LA ROCHE | 2016-05-25 | — | — | CN | disclosed |