Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070110 | 0.72 | ALDH1A1 (0.42) | HDAC1HDAC6ALDH1A1CYP1A2TDP1 | |
| SCHEMBL902623 | 0.72 | ALDH1A1 (0.66) | HDAC1HDAC6ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9015895 | 0.71 | KMT2A (0.42) | ALDH1A1CYP1A2TDP1L3MBTL1GAA | |
| SCHEMBL10712715 | 0.70 | ALDH1A1 (0.41) | ALDH1A1CYP1A2TDP1L3MBTL1GAA | |
| SCHEMBL10525572 | 0.69 | HDAC1 (0.63) | HDAC1HDAC6AOX1ALDH1A1KDM4E | |
| SCHEMBL461849 | 0.68 | IKBKB (0.60) | HDAC1HDAC6ALDH1A1PARP1KDM4E | |
| SCHEMBL30661004 | 0.68 | IKBKB (0.60) | HDAC1HDAC6ALDH1A1PARP1KDM4E | |
| SCHEMBL28464631 | 0.68 | HDAC1 (0.49) | HDAC1HDAC6AOX1ALDH1A1PARP1 | |
| SCHEMBL7030506 | 0.67 | KDM4E (0.56) | HDAC1HDAC6AOX1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL31161184 | 0.67 | IKBKB (0.58) | HDAC1HDAC6ALDH1A1PARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693609-A | Polysubstitution phenyl alkyl amino acridine-4-amide compound and preparing method and purpose thereof | 清华大学深圳研究生院 | 2016-06-22 | — | — | CN | claimed |
| CN-105693609-B | Polysubstituted phenyl alkylamino acridone -4- amides compound and its preparation method and application | 清华大学深圳研究生院 | 2019-03-05 | — | — | CN | disclosed |
| CN-105693609-B | Polysubstituted phenyl alkylamino acridone -4- amides compound and its preparation method and application | 清华大学深圳研究生院 | 2019-03-05 | — | — | CN | disclosed |
| CN-105693609-B | Polysubstituted phenyl alkylamino acridone -4- amides compound and its preparation method and application | 清华大学深圳研究生院 | 2019-03-05 | — | — | CN | disclosed |
| CN-105693609-A | Polysubstitution phenyl alkyl amino acridine-4-amide compound and preparing method and purpose thereof | 清华大学深圳研究生院 | 2016-06-22 | — | — | CN | disclosed |