Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | GRK6 | P43250 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28833548 | 0.87 | KDM4E (0.57) | KDM4EPOLBTSHRNR1H2NR1H3 | |
| SCHEMBL28095619 | 0.87 | KDM4E (0.57) | KDM4EPOLBTSHRNR1H2NR1H3 | |
| SCHEMBL17279690 | 0.87 | NR1H2 (0.60) | KDM4EPOLBTSHRNR1H2NR1H3 | |
| SCHEMBL28096011 | 0.85 | KDM4E (0.55) | KDM4EPOLBTSHRNR1H2NR1H3 | |
| SCHEMBL15117068 | 0.85 | KDM4E (0.67) | KDM4ENR1H2NR1H3ADORA2AADORA1 | |
| SCHEMBL17280055 | 0.84 | KDM4E (0.60) | KDM4EPOLBTSHRNR1H2NR1H3 | |
| SCHEMBL28075481 | 0.84 | KDM4E (0.57) | KDM4EPOLBTSHRNR1H2NR1H3 | |
| SCHEMBL28096010 | 0.82 | KDM4E (0.55) | KDM4EPOLBTSHRGRK6HSD17B10 | |
| SCHEMBL28096008 | 0.82 | KDM4E (0.55) | KDM4EPOLBTSHRNR1H2NR1H3 | |
| SCHEMBL28095606 | 0.82 | KDM4E (0.55) | KDM4EPOLBTSHRNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008557-B | 3,6- diaryl-[1,2,4] triazole simultaneously purposes of [3,4-b] [1,3,4] thiadiazole compound as tumor cell proliferation inhibitor | 沈阳药科大学 | 2019-03-01 | — | — | CN | claimed |
| CN-106243130-B | 3,6- diaryl-[1,2,4] triazole simultaneously [3,4-b] [1,3,4] diazthines compound and application thereof | 沈阳药科大学 | 2019-03-01 | — | — | CN | claimed |
| CN-106243130-A | 3,6 diaryl [1,2,4] triazole also [3,4 b] [1,3,4] diazthines compound and application thereof | 沈阳药科大学 | 2016-12-21 | — | — | CN | claimed |
| CN-106008557-A | Application of 3,6-diaryl-[1,2,4] triazolo[3,4-b][1,3,4] thiadiazole compound as tumor cell proliferation inhibitor | 沈阳药科大学 | 2016-10-12 | — | — | CN | claimed |
| CN-106008557-B | 3,6- diaryl-[1,2,4] triazole simultaneously purposes of [3,4-b] [1,3,4] thiadiazole compound as tumor cell proliferation inhibitor | 沈阳药科大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-106243130-B | 3,6- diaryl-[1,2,4] triazole simultaneously [3,4-b] [1,3,4] diazthines compound and application thereof | 沈阳药科大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-106243130-A | 3,6 diaryl [1,2,4] triazole also [3,4 b] [1,3,4] diazthines compound and application thereof | 沈阳药科大学 | 2016-12-21 | — | — | CN | disclosed |
| CN-106008557-A | Application of 3,6-diaryl-[1,2,4] triazolo[3,4-b][1,3,4] thiadiazole compound as tumor cell proliferation inhibitor | 沈阳药科大学 | 2016-10-12 | — | — | CN | disclosed |