Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 14/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL27951956 | 0.93 | GPR35 (0.50) | GPR35MAOBLMNATP53MAPT | |
| SCHEMBL28917577 | 0.88 | MAOB (0.51) | GPR35MAOBLMNATP53MAPT | |
| SCHEMBL27951959 | 0.85 | ALDH1A1 (0.48) | GPR35MAOBLMNATP53MAPT | |
| SCHEMBL27951954 | 0.81 | MAOB (0.55) | MAOBLMNATP53MAPTTDP1 | |
| SCHEMBL22001521 | 0.79 | TP53 (0.41) | GPR35MAOBLMNATP53MAPT | |
| SCHEMBL22001512 | 0.76 | TNF (0.44) | GPR35MAOBLMNATP53MAPT | |
| SCHEMBL22001386 | 0.76 | LMNA (0.43) | GPR35MAOBLMNATP53MAPT | |
| SCHEMBL22001263 | 0.76 | TP53 (0.39) | GPR35MAOBLMNATP53MAPT | |
| SCHEMBL22001513 | 0.76 | TP53 (0.39) | GPR35MAOBLMNATP53MAPT | |
| SCHEMBL22001545 | 0.73 | TP53 (0.37) | GPR35MAOBLMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626730-B | A kind of preparation method of Coumarin-3-carboxylic ester derivant | 安徽师范大学 | 2016-08-17 | — | — | CN | disclosed |