Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.87 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.87 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.87 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.87 |
| ▸ | TSHR | P16473 | 1/20 | 0.87 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.87 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.87 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.87 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lonidamine SCHEMBL29350056 | 0.93 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| Lonidamine SCHEMBL29351122 | 0.93 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| Lonidamine SCHEMBL7134 | 0.93 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL31566279 | 0.86 | CYP1A2 (0.82) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL21121979 | 0.86 | CYP1A2 (0.82) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| Lonidamine SCHEMBL28086501 | 0.86 | CYP1A2 (0.85) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| Lonidamine SCHEMBL5483035 | 0.85 | CYP1A2 (0.83) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL19497411 | 0.84 | CYP1A2 (0.78) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| Tolnidamine SCHEMBL1604178 | 0.84 | CYP1A2 (0.78) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL14584151 | 0.84 | CYP1A2 (0.82) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109154005-A | Multigenomic retroviral vector formulations and methods and systems for producing and using the same | 免疫设计股份有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-108430583-A | The method for treating disease and illness using interleukin-10 | 阿尔莫生物科技股份有限公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-108025040-A | The method that disease and illness are treated using interleukin-10 | 阿尔莫生物科技股份有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-106084040-A | WNT bonding agent, the compositions comprising it and treatment and manufacture method | 昂考梅德药品有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105848674-A | Methods of using interleukin-10 for the treatment of diseases and disorders | 阿尔莫生物科技股份有限公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-102917721-B | WNT antagonists and methods of treatment and screening | 昂考梅德药品有限公司 | 2016-07-06 | — | — | CN | disclosed |