Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.52 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lonidamine SCHEMBL29350056 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| Lonidamine SCHEMBL7134 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| Lonidamine SCHEMBL28075715 | 0.93 | CYP1A2 (0.87) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| Lonidamine SCHEMBL28086501 | 0.92 | CYP1A2 (0.85) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| Lonidamine SCHEMBL5483035 | 0.91 | CYP1A2 (0.83) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL31566279 | 0.90 | CYP1A2 (0.82) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL14584151 | 0.90 | CYP1A2 (0.82) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL21121979 | 0.90 | CYP1A2 (0.82) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL30949037 | 0.90 | CYP1A2 (0.81) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR | |
| SCHEMBL1051466 | 0.90 | CYP1A2 (0.81) | CYP1A2CYP3A4CYP2C9CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624020-B2 | Compositions and methods for preparing and using azetidines | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2026-05-12 | — | — | US | claimed |
| EP-4040487-B1 | DISPLAY DEVICE | SAMSUNG DISPLAY CO LTD (KR) | 2026-01-21 | — | — | EP | claimed |
| EP-3181125-B1 | CAPSULE FORMULATION | CAPSUGEL BELGIUM NV (BE) | 2025-02-19 | — | — | EP | claimed |
| CN-118397172-A | CT image STL three-dimensional reconstruction method and device based on U-Net | 湖北英库科技有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-113552441-B | Single-phase earth fault detection method and device | 南京南瑞继保电气有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117241818-A | Combination therapy of amuc_1100 and immune checkpoint modulator for the treatment of cancer | 和度生物技术(上海)有限公司 | 2023-12-15 | — | — | CN | claimed |
| EP-4277659-A1 | COMBINATION THERAPIES OF AMUC_1100 AND IMMUNE CHECKPOINT MODULATORS FOR USE IN TREATING CANCERS | Commbio Therapeutics Co., Ltd. (CN) | 2023-11-22 | — | — | EP | claimed |
| CN-113845478-B | Intermediate, and preparation method and application thereof | 四川大学 | 2023-11-21 | — | — | CN | claimed |
| CN-116731072-A | Lonidamine prodrug compound, preparation method and application thereof | 中国海洋大学 | 2023-09-12 | — | — | CN | claimed |
| WO-2023096206-A1 | METHOD FOR PREPARING URETHANE-BASED PREPOLYMER | 수경화학 주식회사 | 2023-06-01 | — | — | WO | claimed |
| CN-116056690-A | Compositions and methods for the treatment and prevention of coronavirus infections | 新概念医疗有限公司 | 2023-05-02 | — | — | CN | claimed |
| US-20230121082-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2023-04-20 | — | — | US | claimed |
| US-11512072-B2 | Compositions and methods for preparing and using azetidines | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2022-11-29 | — | — | US | claimed |
| WO-2022169248-A1 | NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR | 주식회사 엘지화학 | 2022-08-11 | — | — | WO | claimed |
| WO-2022127805-A1 | COMBINATION THERAPIES OF AMUC_1100 AND IMMUNE CHECKPOINT MODULATORS FOR USE IN TREATING CANCERS | COMMBIO THERAPEUTICS CO., LTD. (CN) | 2022-06-23 | — | — | WO | claimed |
| CN-112058237-B | Preparation method of chiral metal organic framework material and application of chiral metal organic framework material in tetracycline hydrochloride sustained release | 蚌埠学院 | 2022-06-17 | — | — | CN | claimed |
| WO-2022092490-A1 | COOLING LIQUID COMPOSITION FOR ELECTRIC VEHICLE | 주식회사 케이디파인켐 | 2022-05-05 | — | — | WO | claimed |
| EP-4744676-A2 | BACTERIA ENGINEERED TO REDUCE HYPERPHENYLALANINEMIA | Synlogic Operating Company, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| CN-113967267-A | Endoplasmic reticulum targeting of fatty acid modified albumin and uses thereof | 四川大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-106250402-B | Website classification method and device | 新华三技术有限公司 | 2022-01-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11512072-B2 | Compositions and methods for preparing and using azetidines | DGKA, DGKK, PRKG2 | CYP1A2 2261/4885CYP3A4 2854/4885CYP2C9 1115/4885 |
| US-12624020-B2 | Compositions and methods for preparing and using azetidines | PRKAR2A, GRK2, GRK6 | CYP1A2 2660/4885CYP3A4 3051/4885CYP2C9 1730/4885 |
| US-20230121082-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | DGKA, DGKK, PRKG2 | CYP1A2 2261/4885CYP3A4 2854/4885CYP2C9 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.