Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aminobenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071833 | 0.93 | AKR1C1 (0.75) | AKR1C1AKR1C3AKR1C2KMT2AMEN1 | |
| SCHEMBL1416571 | 0.90 | AKR1C1 (0.81) | AKR1C1AKR1C3AKR1C2KMT2AMEN1 | |
| SCHEMBL9298399 | 0.90 | AKR1C1 (0.81) | AKR1C1AKR1C3AKR1C2KMT2AMEN1 | |
| SCHEMBL4463208 | 0.88 | AKR1C1 (0.78) | AKR1C1AKR1C3AKR1C2KMT2AMEN1 | |
| SCHEMBL7934875 | 0.86 | AKR1C1 (0.62) | AKR1C1AKR1C3AKR1C2KMT2AMEN1 | |
| SCHEMBL181529 | 0.84 | AKR1C1 (1.00) | AKR1C1AKR1C3AKR1C2KMT2AMEN1 | |
| SCHEMBL39275 | 0.84 | AKR1C1 (1.00) | AKR1C1AKR1C3AKR1C2KMT2AMEN1 | |
| SCHEMBL290469 | 0.84 | AKR1C1 (1.00) | AKR1C1AKR1C3AKR1C2KMT2AMEN1 | |
| SCHEMBL27448137 | 0.82 | AKR1C1 (0.96) | AKR1C1AKR1C3AKR1C2KMT2AMEN1 | |
| Aminobenzoic Acid SCHEMBL5058591 | 0.80 | TSHR (0.70) | KMT2AMEN1POLBALDH1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105120828-B | Cosmetic composition in the form of a gel | 莱雅公司 | 2019-01-29 | — | — | CN | claimed |
| CN-105848626-A | Transparent composition containing oil and microcapsules | 莱雅公司 | 2016-08-10 | — | — | CN | disclosed |