Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364624 | 0.82 | GSK3B (0.61) | CES2CES1PTPN1CA1CA2 | |
| SCHEMBL8554736 | 0.80 | CES2 (0.52) | CES2CES1PTPN1CA1CA2 | |
| SCHEMBL29170482 | 0.80 | CES2 (0.52) | CES2CES1PTPN1CA1CA2 | |
| SCHEMBL2319435 | 0.80 | CES2 (0.52) | CES2CES1PTPN1CA1CA2 | |
| SCHEMBL28636492 | 0.80 | CES2 (0.52) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL1481505 | 0.80 | CES2 (0.52) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL1938267 | 0.78 | CES2 (0.50) | CES2CES1PTPN1CA1CA2 | |
| SCHEMBL5151026 | 0.78 | CES2 (0.50) | CES2CES1PTPN1CA1CA2 | |
| SCHEMBL28121319 | 0.78 | GSK3B (0.42) | CA1CA2GSK3BNPC1RAB9A | |
| SCHEMBL27607377 | 0.78 | CES2 (0.50) | CES2CES1PTPN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958487-B | Benzoic acid derivative as EIF4E inhibitor | 霍夫曼-拉罗奇有限公司 | 2016-07-13 | — | — | CN | disclosed |