SCHEMBL28076009

SCHEMBL28076009

O=C(Cc1cscn1)OC(=O)Cc1cscn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.47
MAPK1 P28482 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
GAA P10253 2/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MAPT P10636 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
SLC6A3 Q01959 4/20 0.37
GPR142 Q7Z601 1/20 0.34
GRM5 P41594 1/20 0.33
TSHR P16473 1/20 0.32
PDE10A Q9Y233 1/20 0.32
CTSK P43235 1/20 0.32
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28076010 0.89 MAPK1 (0.44) PKMMAPK1NPSR1GAAALDH1A1
SCHEMBL5672910 0.85 MAPK1 (0.47) PKMMAPK1NPSR1GAAALDH1A1
SCHEMBL6964768 0.85 PKM (0.45) PKMMAPK1NPSR1GAAALDH1A1
SCHEMBL27590315 0.85 PKM (0.45) PKMMAPK1NPSR1GAAALDH1A1
SCHEMBL860903 0.78
SCHEMBL9382209 0.76 SLC6A3 (0.48) PKMMAPK1NPSR1ALDH1A1SMN1; SMN2
SCHEMBL1758875 0.74 PKM (0.46) PKMMAPK1NPSR1GAAALDH1A1
SCHEMBL5539302 0.74 MAPK1 (0.41) PKMMAPK1NPSR1GAAALDH1A1
SCHEMBL21862328 0.73 KDM4E (0.45) PKMMAPK1NPSR1GAAALDH1A1
SCHEMBL19143642 0.73 PKM (0.45) PKMMAPK1NPSR1GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103910749-B A kind of preparation method of cefotiam hydrochloride 中节能万润股份有限公司 2016-06-29 CN disclosed