Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076009 | 0.85 | PKM (0.47) | PKMMAPK1NPSR1GAAALDH1A1 | |
| SCHEMBL5672910 | 0.81 | MAPK1 (0.47) | PKMMAPK1NPSR1GAAALDH1A1 | |
| SCHEMBL27590315 | 0.81 | PKM (0.45) | PKMMAPK1NPSR1GAAALDH1A1 | |
| SCHEMBL28076010 | 0.79 | MAPK1 (0.44) | PKMMAPK1NPSR1GAAALDH1A1 | |
| SCHEMBL860903 | 0.75 | — | — | |
| SCHEMBL4666843 | 0.74 | PKM (0.49) | PKMMAPK1NPSR1GAAALDH1A1 | |
| SCHEMBL9382209 | 0.73 | SLC6A3 (0.48) | PKMMAPK1NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1758875 | 0.72 | PKM (0.46) | PKMMAPK1NPSR1GAAALDH1A1 | |
| SCHEMBL19143642 | 0.70 | PKM (0.45) | PKMMAPK1NPSR1GAAALDH1A1 | |
| SCHEMBL21862328 | 0.70 | KDM4E (0.45) | PKMMAPK1NPSR1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |