Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.41 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | TPO | P07202 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29215038 | 0.78 | RPS6KA5 (0.34) | MTORSMN1; SMN2CYP3A4MAPT | |
| SCHEMBL29563483 | 0.77 | MPO (0.46) | GRM5MTORRPTORMLST8ALKBH2 | |
| SCHEMBL2160327 | 0.77 | MPO (0.46) | GRM5MTORRPTORMLST8ALKBH2 | |
| SCHEMBL3156955 | 0.77 | GRM5 (0.46) | GRM5MTORRPTORMLST8ALKBH2 | |
| SCHEMBL38651177 | 0.77 | MAPT (0.63) | GRM5MTORRPTORMLST8ALKBH2 | |
| SCHEMBL1907360 | 0.77 | MAPT (0.63) | GRM5MTORRPTORMLST8ALKBH2 | |
| SCHEMBL2643353 | 0.77 | GRM5 (0.46) | GRM5MTORRPTORMLST8ALKBH2 | |
| SCHEMBL19119928 | 0.77 | GRM5 (0.46) | GRM5MTORRPTORMLST8ALKBH2 | |
| SCHEMBL8086526 | 0.77 | GRM5 (0.46) | GRM5MTORRPTORMLST8ALKBH2 | |
| SCHEMBL3463942 | 0.76 | GRM5 (0.55) | GRM5MTORRPTORMLST8ALKBH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103947645-B | 1-(pyridin-3-yl)-pyrazoles and 1-(pyrimidine-5-base)-pyrazoles as insecticide | 拜尔农作物科学股份公司 | 2016-07-06 | — | — | CN | disclosed |