Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9438400 | 0.83 | PIN1 (0.50) | PIN1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL28001222 | 0.83 | PIN1 (0.50) | PIN1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL28231157 | 0.81 | PIN1 (0.60) | PIN1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL28165762 | 0.81 | KDM4E (0.47) | PIN1ALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL15903036 | 0.78 | PIN1 (0.51) | PIN1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL10645455 | 0.77 | ALDH1A1 (0.67) | PIN1ALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL2326248 | 0.77 | MAPT (0.64) | PIN1ALDH1A1MAPTPOLBHPGD | |
| SCHEMBL28972085 | 0.76 | PIN1 (0.55) | PIN1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL28441538 | 0.74 | KDM4E (0.41) | PIN1ALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL27467850 | 0.74 | KDM4E (0.42) | PIN1ALDH1A1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104262159-B | A kind of synthetic method of ortho-nitrophenyl phenolic compound | 浙江工业大学 | 2016-08-10 | — | — | CN | disclosed |