Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28165762 | 0.88 | KDM4E (0.47) | KDM4ENPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL4361112 | 0.88 | KDM4E (0.47) | KDM4ENPC1SCN8AL3MBTL1MEN1 | |
| SCHEMBL28433387 | 0.81 | KDM4E (0.46) | KDM4ENPC1ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL28441538 | 0.80 | KDM4E (0.41) | KDM4ENPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL28709826 | 0.80 | KDM4E (0.41) | KDM4ENPC1ALDH1A1CYP2C19SCN8A | |
| SCHEMBL28444325 | 0.80 | KDM4E (0.39) | KDM4ENPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL15986584 | 0.78 | NPC1 (0.44) | KDM4ENPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL28439921 | 0.76 | KMT2A (0.41) | KDM4ENPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL28442218 | 0.76 | KDM4E (0.39) | KDM4ENPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL28076103 | 0.74 | PIN1 (0.56) | KDM4ENPC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011251-B | Synthesis method and application of 2- (2-chlorophenoxy) pyridine compound | 温州医科大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-1134431-C | 2,4-diaminopyrimidine derivatives as dopamine D4 receptor antagonists | ��˹��ŵ�� | 2004-01-14 | — | — | CN | disclosed |
| CN-1218466-A | 2,4-diaminopyrimidine derivatives as dopamine d4 receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 1999-06-02 | — | — | CN | disclosed |