Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 4/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186066 | 0.92 | OPRM1 (0.37) | MPOCNR2EGFRKDRKIT | |
| Trifluoroacetic Acid SCHEMBL186045 | 0.87 | MAPT (0.41) | MPOEGFRDHODH | |
| Trifluoroacetic Acid SCHEMBL2811073 | 0.87 | RAB9A (0.42) | MPOCNR2DHODHMAPK10PAX8 | |
| Trifluoroacetic Acid SCHEMBL185821 | 0.86 | FLT3 (0.49) | MPOTAS2R14CNR2EGFRKDR | |
| Trifluoroacetic Acid SCHEMBL2807127 | 0.86 | FLT3 (0.49) | MPOTAS2R14CNR2EGFRKDR | |
| Trifluoroacetic Acid SCHEMBL14856648 | 0.83 | FLT3 (0.38) | MPOCNR2EGFRKDRKIT | |
| Trifluoroacetic Acid SCHEMBL2813582 | 0.83 | CNR2 (0.39) | MPOTAS2R14CNR2EGFRKDR | |
| Trifluoroacetic Acid SCHEMBL185819 | 0.83 | MPO (0.36) | MPOTAS2R14CNR2EGFRKDR | |
| SCHEMBL2807621 | 0.83 | CNR2 (0.40) | MPOTAS2R14CNR2EGFRKDR | |
| Trifluoroacetic Acid SCHEMBL186252 | 0.80 | DHODH (0.40) | MPODHODHPAX8LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-23 | — | — | US | disclosed |
| US-20100240669-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | MPO 1362/4885TAS2R14 477/4885CNR2 882/4885 |
| US-20100240669-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | MPO 1362/4885TAS2R14 477/4885CNR2 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.