Pyridine

Pyridine

SCHEMBL28076363

CN(C)c1ccc[nH]1.c1ccncc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 1/20 0.37
CHKA P35790 1/20 0.37
TSHR P16473 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2A6 P11509 1/20 0.33
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
GRM5 P41594 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL826964 0.85
Pyridine SCHEMBL15263781 0.72 TSHR (0.41) TSHRNAPRTTDP1SMN1; SMN2TAAR1
Pyridine SCHEMBL28266645 0.71 TSHR (0.39) TSHRNAPRTTDP1SMN1; SMN2TAAR1
Pyridine SCHEMBL28062605 0.71 TSHR (0.39) TSHRNAPRTTDP1SMN1; SMN2TAAR1
Pyridine SCHEMBL28084443 0.71 TSHR (0.39) TSHRNAPRTTDP1SMN1; SMN2TAAR1
SCHEMBL26482661 0.71 MAOA (0.35)
Pyridine SCHEMBL28078338 0.69 TSHR (0.38) TSHRNAPRTTDP1TAAR1ALDH1A1
Pyridine SCHEMBL28095262 0.68 TDP1 (0.41) TSHRNAPRTTDP1CYP2A6SLC6A2
Pyridine SCHEMBL28193201 0.68 TSHR (0.41) TSHRNAPRTTDP1SLC6A2SLC6A4
Pyridine SCHEMBL28270231 0.68 TSHR (0.41) TSHRNAPRTTDP1ALDH1A1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110368988-A A kind of vitamin B12With the difunctional graphite alkene catalysis material of ruthenium complex and its preparation method and application 辽宁大学 2019-10-25 CN claimed
CN-109467886-A A kind of simple function group polyethex amine modification graphene oxide/epoxy resin nano composites of high-strength and high ductility 四川大学 2019-03-15 CN claimed
CN-104284885-B Sulforaphane derived compounds, process for their preparation and their medical, food and cosmetic use 高等科学研究委员会 2018-03-27 CN claimed
CN-104292222-B Novel synthetic method of tebipenem pivoxil side chain 常州锐博生物科技有限公司 2017-05-10 CN claimed
CN-110461823-A SALTS FOR USE IN ELECTROLYTE COMPOSITIONS OR AS ELECTRODE ADDITIVES HYDRO QUEBEC 2019-11-15 CN disclosed
CN-110461824-A Method for producing polymerizable compound and solution ZEON CORP 2019-11-15 CN disclosed
CN-106432747-B Derivative hyperbranched poly glycerine 不列颠哥伦比亚大学 2019-11-05 CN disclosed
CN-110408383-A With distortion to pure organic room temperature phosphorimetry material and its preparation method and application of-receptor structure HKUST SHENZHEN RES INSTITUTE 2019-11-05 CN disclosed
CN-106732772-B Cracking catalyst for 1, 2-dichloroethane, process for producing the same and use thereof 台湾塑胶工业股份有限公司 2019-09-24 CN disclosed
CN-110248941-A The imidazopyridine derivatives that aryl or heteroaryl replace and its purposes as pesticide 拜耳公司 2019-09-17 CN disclosed
CN-106520743-B Recombination hydroxynitrile lyases and its application for being used to prepare optical homochiral cyanalcohol 华东理工大学 2019-08-06 CN disclosed
CN-109970749-A The antiviral compound inhibitor of HCV NS5A 吉利德制药有限责任公司 2019-07-05 CN disclosed
CN-106432747-A Derivatized Hyperbranched Polyglycerols 不列颠哥伦比亚大学 2017-02-22 CN disclosed
CN-106146649-A The polypeptide of additional sugar chain and the medical composition containing this polypeptide 株式会社糖锁工学研究所 2016-11-23 CN disclosed
CN-104487442-B Antiviral Compound Inhibitors of HCV NS5A 吉利德制药有限责任公司 2016-10-26 CN disclosed
CN-106033173-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士施乐株式会社 2016-10-19 CN disclosed
CN-102905703-B As TLR2 agonist for treating compound (lipopeptid based on cysteine) and the compositions of infection, inflammation, respiratory disorder etc. 诺华股份有限公司 2016-09-28 CN disclosed
CN-103958465-B Phenyl derivatives 小野药品工业株式会社 2016-08-31 CN disclosed
CN-102906157-B Derivatized hyperbranched polyglycerols 不列颠哥伦比亚大学 2016-08-24 CN disclosed
CN-103917531-B The preparation of MFG intermediate 桑多斯股份公司 2016-08-24 CN disclosed