Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714973 | 0.83 | CYP2C19 (0.54) | RECQLPOLBCYP3A4PARP1MAPT | |
| SCHEMBL649489 | 0.82 | TDP1 (0.62) | RECQLPOLBCYP3A4PARP1MAPT | |
| SCHEMBL28312400 | 0.82 | TDP1 (0.62) | RECQLPOLBCYP3A4PARP1MAPT | |
| SCHEMBL3020894 | 0.80 | POLB (0.60) | RECQLPOLBCYP3A4PARP1MAPT | |
| SCHEMBL10693090 | 0.80 | POLB (0.60) | RECQLPOLBCYP3A4PARP1MAPT | |
| SCHEMBL28856431 | 0.79 | PLA2G10 (0.61) | RECQLPOLBCYP3A4PARP1MAPT | |
| SCHEMBL25369373 | 0.79 | PLA2G2A (0.40) | RECQLPOLBCYP3A4PARP1MAPT | |
| SCHEMBL193835 | 0.78 | HTR2A (0.52) | TSHRTDP1L3MBTL1CYP2D6 | |
| Acetic Acid SCHEMBL28538311 | 0.77 | MTNR1A (0.52) | POLBKMT2ACYP2D6 | |
| Ammonia Solution, Strong SCHEMBL28352255 | 0.76 | HTR2A (0.50) | TSHRTDP1L3MBTL1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-B | Aminoheteroaryl benzamide as kinase inhibitor | 诺华股份有限公司 | 2018-11-27 | — | — | CN | disclosed |
| CN-105658646-A | Aminoheteroaryl benzamides as kinase inhibitors | 诺华股份有限公司 | 2016-06-08 | — | — | CN | disclosed |