Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.48 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193835 | 0.97 | HTR2A (0.52) | HTR2ATAAR1TRPA1HRH1LMNA | |
| Hydrochloric Acid SCHEMBL6251948 | 0.94 | HTR2A (0.50) | HTR2ATAAR1TRPA1HRH1LMNA | |
| Dimethylamine SCHEMBL10622831 | 0.87 | HTR2A (0.52) | HTR2ATAAR1TRPA1HRH1LMNA | |
| SCHEMBL11552637 | 0.87 | HTR2A (0.44) | HTR2ATAAR1TRPA1HRH1LMNA | |
| Acetic Acid SCHEMBL28538311 | 0.85 | MTNR1A (0.52) | HTR2ATRPA1HRH1LMNACYP2D6 | |
| SCHEMBL11359363 | 0.85 | CHRNB2 (0.61) | HTR2ATAAR1TRPA1LMNACYP2D6 | |
| SCHEMBL10936369 | 0.83 | TSHR (0.56) | HTR2ATAAR1TRPA1HRH1LMNA | |
| SCHEMBL3398681 | 0.83 | HTR2A (0.63) | HTR2ATAAR1TRPA1TDP1 | |
| SCHEMBL7019079 | 0.83 | CNR1 (0.49) | HTR2ATAAR1TRPA1HRH1LMNA | |
| SCHEMBL28028823 | 0.83 | CACNA2D1 (0.44) | HTR2ATAAR1TRPA1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107162982-B | Imidazole compounds with anticancer activity and derivatives thereof | 广东药科大学 | 2020-02-11 | — | — | CN | disclosed |