Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 7/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997728 | 0.96 | HTR4 (0.46) | HTR4GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL28076703 | 0.91 | SLC6A2 (0.47) | HTR4GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL28076529 | 0.91 | CCR5 (0.41) | HTR4ACHEDRD4TSHRMEN1 | |
| SCHEMBL27997741 | 0.90 | HTR4 (0.42) | HTR4GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL27997523 | 0.88 | HTR4 (0.45) | HTR4ACHETSHRMEN1KMT2A | |
| SCHEMBL28956404 | 0.88 | SLC6A2 (0.47) | HTR4GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL27997533 | 0.88 | SLC6A2 (0.47) | HTR4GRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL27997529 | 0.88 | GMNN (0.48) | HTR4GRIN1GRIN2BADRA1DADRA1A | |
| SCHEMBL28076702 | 0.88 | MCHR1 (0.49) | GRIN1GRIN2BGRIN2DGRIN3BADRA1D | |
| SCHEMBL27997528 | 0.87 | HTR4 (0.42) | HTR4ACHEDRD4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | claimed |