Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997741 | 0.92 | HTR4 (0.42) | ADRA1DADRA1AADRA1BGRIN2DGRIN3B | |
| SCHEMBL28956404 | 0.91 | SLC6A2 (0.47) | SLC6A4SLC6A3SLC6A2ADRA1DADRA1A | |
| SCHEMBL27997728 | 0.91 | HTR4 (0.46) | ADRA1DADRA1AADRA1BGRIN2DGRIN3B | |
| SCHEMBL27997533 | 0.91 | SLC6A2 (0.47) | SLC6A4SLC6A3SLC6A2ADRA1DADRA1A | |
| SCHEMBL27997525 | 0.91 | MEN1 (0.43) | SLC6A4ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL27997721 | 0.91 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL27997528 | 0.91 | HTR4 (0.42) | MEN1KMT2AALDH1A1DRD2DRD4 | |
| SCHEMBL27997732 | 0.91 | SLC6A4 (0.41) | MCHR1SLC6A4SLC6A3SLC6A2GRIN2B | |
| SCHEMBL28816405 | 0.88 | ACHE (0.45) | MEN1KMT2AALDH1A1DRD2DRD4 | |
| SCHEMBL27997523 | 0.88 | HTR4 (0.45) | MEN1KMT2AALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | claimed |
| CN-105646331-B | Piperidine compounds, the medical composition and its use containing the compound | 爱思开生物制药株式会社 | 2018-07-03 | — | — | CN | disclosed |
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | disclosed |