SCHEMBL28076581

SCHEMBL28076581

Oc1cc(Br)c(Br)c2cc3ccccc3cc12

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 3/20 0.47
POLB P06746 1/20 0.45
TRPM4 Q8TD43 1/20 0.43
CYP1A2 P05177 2/20 0.37
CYP2A6 P11509 1/20 0.37
ALOX5 P09917 1/20 0.35
PTPN22 Q9Y2R2 1/20 0.34
NQO1 P15559 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP1B1 Q16678 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28245617 0.80 CYP2A6 (0.41) NQO2POLBCYP1A2CYP2A6NQO1
SCHEMBL28118837 0.77 POLB (0.47) NQO2POLBTRPM4CYP1A2CYP2A6
SCHEMBL2265917 0.77 CYP2A6 (0.50) NQO2POLBCYP1A2CYP2A6NQO1
SCHEMBL14092891 0.75 CYP2A6 (0.44) NQO2POLBCYP1A2CYP2A6NQO1
SCHEMBL27569032 0.74 CYP2A6 (0.48) NQO2POLBCYP1A2CYP2A6NQO1
SCHEMBL28634296 0.74 IDO1 (0.58) NQO2POLBTRPM4CYP1A2ALOX5
SCHEMBL29681720 0.74 IDO1 (0.58) NQO2POLBTRPM4CYP1A2ALOX5
SCHEMBL392914 0.74 IDO1 (0.58) NQO2POLBTRPM4CYP1A2ALOX5
SCHEMBL2352895 0.73 PTPN22 (0.50) NQO2TRPM4CYP1A2ALOX5PTPN22
SCHEMBL2219635 0.72 ALDH1A1 (0.48) NQO2POLBTRPM4CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105753712-A Synthesis method for 1-nitro-2,3-dibromo-4-hydroxyanthraquinone 常州大学 2016-07-13 CN disclosed