Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076775 | 0.90 | HTR1A (0.43) | HTR1ASLC6A4GPR6 | |
| SCHEMBL28076591 | 0.86 | HTR1A (0.46) | HTR1ASLC6A4 | |
| SCHEMBL28830777 | 0.86 | HTR1A (0.56) | HTR1ASLC6A4 | |
| SCHEMBL28076596 | 0.81 | HTR1A (0.54) | HTR1ASLC6A4 | |
| SCHEMBL28076639 | 0.78 | HTR1A (0.55) | HTR1ASLC6A4 | |
| SCHEMBL28076773 | 0.75 | GPR6 (0.38) | HTR1ASLC6A4GPR6 | |
| SCHEMBL3577962 | 0.71 | RYR2 (0.49) | HTR1ASLC6A4 | |
| SCHEMBL30323089 | 0.69 | GPR6 (0.59) | HTR1ASLC6A4GPR6 | |
| SCHEMBL20524624 | 0.69 | GPR6 (0.59) | HTR1ASLC6A4GPR6 | |
| SCHEMBL3586208 | 0.68 | MEN1 (0.43) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | disclosed |