Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.54 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076591 | 0.89 | HTR1A (0.46) | HTR1ASLC6A4KMT2A | |
| SCHEMBL28076775 | 0.87 | HTR1A (0.43) | HTR1ASLC6A4 | |
| SCHEMBL28830777 | 0.83 | HTR1A (0.56) | HTR1ASLC6A4 | |
| SCHEMBL28076772 | 0.81 | HTR1A (0.43) | HTR1ASLC6A4 | |
| SCHEMBL28076639 | 0.80 | HTR1A (0.55) | HTR1ASLC6A4 | |
| SCHEMBL28076593 | 0.80 | HTR1A (0.45) | HTR1ASLC6A4CCR3CCR5 | |
| SCHEMBL3577962 | 0.76 | RYR2 (0.49) | HTR1ASLC6A4 | |
| SCHEMBL28076798 | 0.75 | HTR1A (0.55) | HTR1ASLC6A4CCR3 | |
| SCHEMBL28830757 | 0.73 | TSHR (0.60) | MEN1KMT2A | |
| SCHEMBL28076884 | 0.73 | SLC6A4 (0.52) | HTR1ASLC6A4CCR3CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646331-B | Piperidine compounds, the medical composition and its use containing the compound | 爱思开生物制药株式会社 | 2018-07-03 | — | — | CN | disclosed |
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | disclosed |