Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 4/20 | 0.51 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629483 | 0.81 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL28831015 | 0.80 | ALOX5 (0.62) | ALOX5TRPM8 | |
| SCHEMBL28315188 | 0.79 | MAPT (0.55) | ALOX5 | |
| SCHEMBL1954805 | 0.79 | ALOX5 (0.56) | ALOX5TRPM8 | |
| SCHEMBL28077371 | 0.78 | TRPM8 (0.64) | TRPM8 | |
| SCHEMBL15049252 | 0.77 | CDC7 (0.67) | ALOX5TRPM8 | |
| SCHEMBL9628733 | 0.77 | ALOX5 (1.00) | ALOX5TRPM8 | |
| SCHEMBL13801077 | 0.74 | ALOX5 (0.50) | ALOX5APPSULT1A1TRPM8 | |
| SCHEMBL17374845 | 0.72 | TRPM8 (0.71) | ALOX5TRPM8 | |
| SCHEMBL28077336 | 0.72 | HDAC9 (0.39) | ALOX5TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334544-B | Benzimidazole proline derivative | 埃科特莱茵药品有限公司 | 2016-10-19 | — | — | CN | disclosed |