Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 9/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28831133 | 0.80 | CA3 (0.39) | TRPM8ALOX5LMNA | |
| SCHEMBL28077397 | 0.77 | GRM2 (0.37) | ESR2ESR1ALOX5MAPT | |
| SCHEMBL28077415 | 0.76 | TRPM8 (0.50) | TRPM8ALOX5LMNAMAPT | |
| SCHEMBL14960141 | 0.74 | TLR8 (0.39) | HDAC9MAPTHSP90AB1 | |
| SCHEMBL3436697 | 0.74 | MAPT (0.41) | HDAC9LMNAMAPT | |
| SCHEMBL19936382 | 0.73 | HDAC9 (0.39) | HDAC9LMNAMAPTHSP90AB1 | |
| SCHEMBL3436650 | 0.73 | SMN1; SMN2 (0.54) | HDAC9MAPT | |
| SCHEMBL31120341 | 0.72 | MAPT (0.57) | LMNAMAPT | |
| SCHEMBL16806003 | 0.72 | ALOX5 (0.42) | HDAC9ALOX5 | |
| SCHEMBL28077209 | 0.72 | ALOX5 (0.62) | TRPM8ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334544-B | Benzimidazole proline derivative | 埃科特莱茵药品有限公司 | 2016-10-19 | — | — | CN | disclosed |