SCHEMBL28077218

SCHEMBL28077218

Cc1cc(-n2cnnc2)ccc1-c1ccc(-n2cnnc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH5 P11766 6/20 0.50
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
QPCT Q16769 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
ESR2 Q92731 2/20 0.35
HSD17B1 P14061 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
CASP1 P29466 1/20 0.34
RECQL P46063 1/20 0.34
CASP7 P55210 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12841361 0.78 CYP1A2 (0.47) CYP1A2CYP2C9QPCTL3MBTL1KDM4E
SCHEMBL28106810 0.75 CYP1A2 (0.56) ADH5CYP1A2CYP2C9QPCTMAPT
SCHEMBL10053600 0.73 L3MBTL1 (0.49) CYP1A2CYP2C9L3MBTL1KDM4EALDH1A1
SCHEMBL7314884 0.73 KDM4E (0.50) CYP1A2CYP2C9L3MBTL1KDM4EALDH1A1
SCHEMBL28002115 0.72 CYP1A2 (0.64) ADH5CYP1A2CYP2C9QPCTMAPT
SCHEMBL3344599 0.71 KMT2A (0.51) CYP1A2CYP2C9QPCTL3MBTL1KDM4E
SCHEMBL6518759 0.71 CYP2C9 (0.58) CYP1A2CYP2C9QPCTL3MBTL1KDM4E
SCHEMBL10053481 0.69 PKM (0.48) CYP1A2CYP2C9L3MBTL1ALDH1A1MAPT
SCHEMBL17630180 0.69 ADH5 (0.64) ADH5CYP1A2HSD17B10KMT2APDE3B
SCHEMBL17630071 0.68 ADH5 (1.00) ADH5ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105622529-A 4-(4-nitrophenyl)-4H-1,2,4-triazole dimeric silver complex single-crystal and application UNIV TIANJIN 2016-06-01 CN disclosed