SCHEMBL28077477

SCHEMBL28077477

CC(C)(CC(=O)O)C(=O)O.CCCC(O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
ACACB O00763 1/20 0.40
ACACA Q13085 1/20 0.40
CHRM1 P11229 2/20 0.38
ADRA1A P35348 2/20 0.38
HMGCR P04035 1/20 0.38
TBXA2R P21731 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HSPD1 P10809 1/20 0.38
BLM P54132 1/20 0.38
HSPE1 P61604 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
AKR1A1 P14550 1/20 0.37
CHRM3 P20309 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HRH1 P35367 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL28188759 0.87 ALDH1A1 (0.40) TSHRALDH1A1
SCHEMBL29544360 0.82 TET2 (0.47) CYP2D6TSHRCYP2C19HIF1ACHRM1
Pivalate SCHEMBL1142631 0.81 CHRM1 (0.44) CYP2D6TSHRCYP2C19HIF1AACACB
Citric Acid SCHEMBL30150822 0.80 ALDH1A1 (0.60) CYP2D6TSHRCYP2C19HIF1ACHRM1
SCHEMBL27150754 0.80 CHRM1 (0.38) CYP2D6TSHRCYP2C19HIF1ACHRM1
SCHEMBL83915 0.80 TSHR (0.60) CYP2D6TSHRCYP2C19HIF1AACACB
Hydrochloric Acid SCHEMBL4137653 0.80 TSHR (0.60) CYP2D6TSHRCYP2C19HIF1AACACB
Ammonia Solution, Strong SCHEMBL10868076 0.78 TSHR (0.57) CYP2D6TSHRCYP2C19HIF1AACACB
SCHEMBL28478983 0.78 TSHR (0.57) CYP2D6TSHRCYP2C19HIF1AACACB
SCHEMBL8844260 0.78 TSHR (0.57) CYP2D6TSHRCYP2C19HIF1AACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105367771-B A kind of lactyl aliphatic random copolymer and preparation method thereof 中国科学院长春应用化学研究所 2018-02-13 CN disclosed
CN-104356374-B A kind of aliphatic-PLA segmented copolymer 中国科学院长春应用化学研究所 2016-08-24 CN disclosed