Styrene

Styrene

SCHEMBL28077574

C=C(CCCCCCCCCCCC)C(=O)OC.C=Cc1ccccc1

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
LMNA P02545 1/20 0.43
ALDH1A1 P00352 2/20 0.43
EGFR P00533 1/20 0.43
EPHX2 P34913 2/20 0.43
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
ASAH1 Q13510 2/20 0.42
SOAT2 O75908 1/20 0.42
SOAT1 P35610 1/20 0.42
TUBB4A P04350 2/20 0.42
TUBB P07437 2/20 0.42
TUBA3C P0DPH7 2/20 0.42
TUBA1B P68363 2/20 0.42
TUBA4A P68366 2/20 0.42
TUBB4B P68371 2/20 0.42
TUBB3 Q13509 2/20 0.42
TUBB2A Q13885 2/20 0.42
TUBB8 Q3ZCM7 2/20 0.42
TUBA3E Q6PEY2 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL2942058 0.99 LMNA (0.44) TDP1LMNAALDH1A1EGFREPHX2
Styrene SCHEMBL6449703 0.88 MEN1 (0.42) TDP1LMNAALDH1A1EGFRTUBB4A
Styrene SCHEMBL1476489 0.88 MEN1 (0.49) TDP1LMNAALDH1A1EGFRCES2
Styrene SCHEMBL9354667 0.87 TDP1 (0.55) TDP1LMNAALDH1A1EGFREPHX2
Styrene SCHEMBL905411 0.87 TDP1 (0.55) TDP1LMNAALDH1A1EGFREPHX2
Styrene SCHEMBL28368789 0.87 TDP1 (0.55) TDP1LMNAALDH1A1EGFREPHX2
Styrene SCHEMBL8350505 0.87 TDP1 (0.55) TDP1LMNAALDH1A1EGFREPHX2
Styrene SCHEMBL1628459 0.87 TDP1 (0.55) TDP1LMNAALDH1A1EGFREPHX2
Styrene SCHEMBL1628229 0.86 LMNA (0.54) TDP1LMNAALDH1A1EGFREPHX2
Benzene SCHEMBL28247800 0.85 GPR84 (0.47) TDP1ALDH1A1EPHX2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105837967-A Expandable vinyl aromatic polymeric compositions 维尔萨利斯股份公司 2016-08-10 CN disclosed