Benzo[D]Thiazole

Benzo[D]Thiazole

SCHEMBL28077640

CC(O)=S.c1ccc2scnc2c1

nearest known ligand 0.73

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.73
HSD17B10 Q99714 1/20 0.73
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
TDP1 Q9NUW8 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 2/20 0.43
HKDC1 Q2TB90 1/20 0.43
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
INSR P06213 1/20 0.35
CSF1R P07333 1/20 0.35
PDGFRB P09619 1/20 0.35
PDGFRA P16234 1/20 0.35
KDR P35968 1/20 0.35
TEK Q02763 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[D]Thiazole SCHEMBL20139457 0.89 ALDH1A1 (0.68) ALDH1A1HSD17B10NPC1RAB9ATDP1
Benzo[D]Thiazole SCHEMBL10587301 0.89 ALDH1A1 (0.73) ALDH1A1HSD17B10NPC1RAB9ATDP1
Benzo[D]Thiazole SCHEMBL27900622 0.88 ALDH1A1 (0.86) ALDH1A1HSD17B10NPC1RAB9ATDP1
Benzo[D]Thiazole SCHEMBL2173015 0.88 ALDH1A1 (0.95) ALDH1A1HSD17B10NPC1RAB9ATDP1
Benzo[D]Thiazole SCHEMBL28487786 0.87 ALDH1A1 (0.66) ALDH1A1HSD17B10NPC1RAB9ATDP1
Benzo[D]Thiazole SCHEMBL27931731 0.86 ALDH1A1 (0.76) ALDH1A1HSD17B10NPC1RAB9ATDP1
Benzo[D]Thiazole SCHEMBL31388426 0.85
Benzo[D]Thiazole SCHEMBL8430 0.85
Benzo[D]Thiazole SCHEMBL451685 0.85
Benzo[D]Thiazole SCHEMBL10847268 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115678637-B Application of two-component ionic liquid as lubricant and water-glycerol lubricant composition thereof 徐州工程学院 2024-03-22 CN claimed
CN-115678637-A Application of two-component ionic liquid as lubricant and water-glycerin lubricant composition thereof 徐州工程学院 2023-02-03 CN claimed
CN-105648483-A High-speed tinning solution and preparation method thereof 济南德锡科技有限公司 2016-06-08 CN claimed
CN-115678637-B Application of two-component ionic liquid as lubricant and water-glycerol lubricant composition thereof 徐州工程学院 2024-03-22 CN disclosed
CN-112969770-B Novel antifreeze and coolant for fuel cells, storage cells and batteries 巴斯夫欧洲公司 2024-02-27 CN disclosed
CN-115678637-A Application of two-component ionic liquid as lubricant and water-glycerin lubricant composition thereof 徐州工程学院 2023-02-03 CN disclosed
CN-105648483-A High-speed tinning solution and preparation method thereof 济南德锡科技有限公司 2016-06-08 CN disclosed